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TARLING-VALLIM Lab

Welcome to the TARLING and VALLIM Labs

Studying cellular and tissue adaptation to lipid changes in health and disease.

Unraveling cholesterol dynamics in immune cells to combat cardiopulmonary diseases.

Discovering novel lipid metabolism regulators in metabolic diseases with omics and gene-targeted approaches.

MEMBERS

ETV Lab members grouped at the base of a staircase in an urban setting on a bright day, smiling and arranged in three rows, all wearing dark blue zip-up jackets with the lab logo on the right side.

PUBLICATIONS

Electron microscopy image of hepatocyte organelles, showing darker, electron-dense mitochondria in the lower left corner, interspersed with thin membranes from the endoplasmic reticulum, and centrally located lighter, peroxisomes with a less dense, homogeneous matrix.
Journal of Lipid Research (JLR) cover page with a brown background, “2024” and the journal name in white within a top-right box, and “ASBMB Journals” in the lower-left corner, featuring a central illustration of the human body focused on the respiratory system, with side panels contrasting health and disease.

Alveolar macrophage lipid burden correlates with clinical improvement in patients with pulmonary alveolar proteinosis

J Lipid Res. 2024

Full publication list
Circulation Research cover page with the journal name displayed at the top on a white horizontal stripe. The central image is a fluorescence microscopy image with a shape resembling an aerial view of Earth, suggesting a continent-like cell structure. A list of article titles appears in the lower-left corner.

RNF130 Regulates LDLR Availability and Plasma LDL Cholesterol Levels

Circ Res. 2023

Full publication list
First page of the scientific article with title on top and a schematic illustration of digestive pathway.

FXR activation protects against NAFLD via bile-acid-dependent reductions in lipid absorption

Cell Metab. 2021

Full publication list
First page of a scientific article with the title at the top, followed by author names, institutional information, and the abstract.

An integrative systems genetic analysis of mammalian lipid metabolism

Nature. 2019

Full publication list
First page of a scientific article with the title at the top, followed by author names, institutional information, and the abstract.

Statin as a novel pharmacotherapy of pulmonary alveolar proteinosis

Nat Commun. 2018

Full publication list
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Check out our multi-omics searchable database.

Decorative images based on the Tarling-Vallim Lab logos

Lab NEWS

CONTACT US

Dissection microscope image of a mouse aorta pinned against a gray background, showing red plaques stained by Oil Red O indicating neutral lipid accumulation in atherosclerotic lesions; a prominent bifurcation on the left displays the largest plaque buildup, with smaller, less abundant plaques extending along the vessel.
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